Genetic Studies of Kanamycin Resistance inStaphylococcus aureus

Genetic studies of kanamycin resistance in Campylobacter jejuni.

Campylobacter jejuni 3H40 and 4B20 harbored 59-kilobase (kb) self-transmissible plasmids encoding resistance to kanamycin and tetracycline. Although the two antibiotic resistances were more frequently inherited together, some transconjugants and ethidium bromide segregants which were resistant to only one of these antibiotics were recovered. The kanamycin-susceptible, tetracycline-resistant seg...

Kanamycin Resistance Cassette for Genetic Manipulation of Treponema denticola.

Treponema denticola has been recognized as an important oral pathogen of the "red complex" bacterial consortium that is associated with the pathogenesis of endodontal and periodontal diseases. However, little is known about the virulence of T. denticola due to its recalcitrant genetic system. The difficulty in genetically manipulating oral spirochetes is partially due to the lack of antibiotic ...

Kanamycin Resistance Cassette for the Genetic Manipulation of Treponema denticola

Evolution of antibiotic resistance genes: the DNA sequence of a kanamycin resistance gene from Staphylococcus aureus.

The kanamycin resistance gene from Staphylococcus aureus has been sequenced and its structure compared with similar genes isolated from Streptomyces fradiae and from two transposons, Tn5 and Tn903, originally isolated from Klebsiella pneumoniae and Salmonella typhimurium, respectively. The genes are all homologous but, since their common ancestor, have undergone extensive divergence, with more ...

Antimicrobial resistance of Staphylococcus aureus: genetic basis.

INTRODUCTION................................................................................................................. 89 Emergence of Multiresislant S. aureus.................................................................................... 89 Genetic Nature of Antimicrobial Resistance ...——....——......—.—......—..—..—.——.—..—.—...—. 90 TRANSFER OF RESISTANCE GENES IN STAPHYLOCOCCI......